期刊: TRENDS IN CELL BIOLOGY, 2022; 32 (10)
N7-methylguanosine (m(7)G) is a significant RNA modification occurring during epigenetic regulation. An increasing number of investigations have prove......
期刊: TRENDS IN CELL BIOLOGY, 2022; 32 (1)
The basic body plan of the mammalian embryo is established through gastrulation, a pivotal early postimplantation event during which the three major g......
期刊: TRENDS IN CELL BIOLOGY, 2022; 32 (4)
Precisely deciphering the cellular plasticity in vivo is essential in understanding many key biological processes. Site-specific recombinases are gene......
期刊: TRENDS IN CELL BIOLOGY, 2022; 32 (9)
Gene transcription and cell metabolism are two fundamental biological pro-cesses that mutually regulate each other. Upregulated or altered expression ......
期刊: TRENDS IN CELL BIOLOGY, 2022; 32 (12)
A recent study showed that RNA transcription is directly involved in DNA homol-ogous recombination (HR). The first step in HR is end resection, which ......
期刊: TRENDS IN CELL BIOLOGY, 2022; 32 (10)
Pluripotent stem cells (PSCs) can self-renew indefinitely in culture while retaining the potential to differentiate into virtually all normal cell typ......
期刊: TRENDS IN CELL BIOLOGY, 2022; 32 (5)
Creatine is a nitrogen-containing organic acid naturally existing in mammals. It can be converted into phosphocreatine to provide energy for muscle an......
期刊: TRENDS IN CELL BIOLOGY, 2022; 32 (1)
Mechanical hallmarks of fibrotic microenvironments are both outcomes and causes of fibrosis progression. Understanding how cells sense and transmit me......
期刊: TRENDS IN CELL BIOLOGY, 2022; 32 (2)
Membrane-cytoskelet on interactions (MCIs) are mediated by actinbinding proteins (ABPs). Ezrin is a crucial ABP that links membranes to actin filament......
期刊: TRENDS IN CELL BIOLOGY, 2022; 32 (1)
Membraneless organelles (MLOs) present as a condensed metastable phase of different proteins and RNAs organized via liquid-liquid phase separation. Re......
期刊: TRENDS IN CELL BIOLOGY, 2022; 32 (3)
Solute carrier transporters (SLCs) mediate nutrient and metabolite cellular homeostasis. Immune cells depend on SLCs to induce rapid and robust meta-b......
期刊: TRENDS IN CELL BIOLOGY, 2022; 32 (11)
Autophagy is a multistage, intracellular process. Here, we highlight a recently identified autophagosomal components recycling (ACR) stage and the rec......
期刊: TRENDS IN CELL BIOLOGY, 2021; 31 (9)
BARD1 directs BRCA1 to DNA damage sites to facilitate homology recombination. Zhou and colleagues have now determined the cryo-electron microscopy (cr......
期刊: TRENDS IN CELL BIOLOGY, 2021; 31 (7)
Given themismatch in size and morphology of intestinal organoids with native intestine, their application in intestinal segment regeneration has yet t......
期刊: TRENDS IN CELL BIOLOGY, 2021; 31 (6)
Autophagy and the ubiquitin-proteasome system (UPS) are two major pathways for protein degradation. The cullin-RING E3 ligases (CRLs) are the largest ......