期刊: BIOTECHNOLOGY JOURNAL, 2021; 16 (9)
Chinese hamster ovary (CHO) cells with a high viable cell density (VCD), resilience to culture stress, and the capacity to continuously express recomb......
期刊: BIOTECHNOLOGY JOURNAL, 2021; 16 (7)
Background The success of biomedical implants in orthopedic and dental applications is usually limited due to insufficient bone-implant integration, a......
期刊: BIOTECHNOLOGY JOURNAL, 2021; 16 (9)
Background Aldo-keto reductases-catalyzed transformations of ketones to chiral alcohols have become an established biocatalytic process step in the ph......
期刊: BIOTECHNOLOGY JOURNAL, 2021; 16 (8)
Background: Corynebacterium glutamicum is an important chassis for industrial applications. The low efficiency of commonly used genome editing methods......
期刊: BIOTECHNOLOGY JOURNAL, 2021; 16 (9)
beta-Defensins are a family of conserved small cationic antimicrobial peptides with different significant biological functions. The majority of mammal......
期刊: BIOTECHNOLOGY JOURNAL, 2021; 16 (7)
Background Probe substrates are an important tool for activity monitoring of human drug metabolizing enzymes such as cytochromes P450 (CYPs). Brief Me......
期刊: BIOTECHNOLOGY JOURNAL, 2021; 16 (8)
Microbial natural products among other functions they play a vital role in the disease prevention in humans, animals and plants. Pseudomonas parafulva......
期刊: BIOTECHNOLOGY JOURNAL, 2021; 16 (7)
Background: With high cell doses required for mesenchymal stromal cell (MSC) clinical trials, there is a need to upgrade technologies that facilitate ......
期刊: BIOTECHNOLOGY JOURNAL, 2021; 16 (9)
The tumor microenvironment (TME) harbors heterogeneous contents and plays critical roles in tumorigenesis, metastasis, and drug resistance. Therefore,......
期刊: BIOTECHNOLOGY JOURNAL, 2021; 16 (8)
Western equine encephalitis virus (WEEV) causes lethal encephalitis in humans and equines, and it poses a serious public health threat in many countri......
期刊: BIOTECHNOLOGY JOURNAL, 2021; 16 (9)
pH regulation is a serious concern in the industrial fermentation process as pH adjustment heavily utilizes acid/base and pollutes the environment. Un......
期刊: BIOTECHNOLOGY JOURNAL, 2021; 16 (7)
beta-farnesene is a sesquiterpenoid with various industrial applications which is now commercially produced by a Saccharomyces cerevisiae strain obtai......
期刊: BIOTECHNOLOGY JOURNAL, ; ()
Chondroitinase ABC I (csABC I) has attracted intensive attention because of its great potential in heparin refining and the enzymatic preparation of l......
期刊: BIOTECHNOLOGY JOURNAL, ; ()
Background Methylorubrum extorquens AM1 can be engineered to convert methanol to value-added chemicals. Most of these chemicals derive from acetyl-CoA......