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Characterization of drug-related impurities using UPLC-QTrap-MS/MS in three scan modes: Application to daptomycin

期刊: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021; 468 ()

A new non-targeted screening strategy was developed for the detection and relative quantification of known and potentially unknown drug-related impuri......

Differentiation of isomers of oxygenated polycyclic aromatic hydrocarbons by laser desorption laser post-ionization time-of-flight mass spectrometry

期刊: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021; 467 ()

Oxygenated polycyclic aromatic hydrocarbons (OPAHs) are mutagenic and ubiquitous pollutants to both humans and environment. Routine analytical methods......

Compound identification via deep classification model for electron- ionization mass spectrometry

期刊: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021; 463 ()

Compound identification in electron-ionization mass spectrometry (EI-MS) is usually achieved by matching the query mass spectrum to the well-collected......

A simple and reliable measurement procedure for determination of glycocholic acid in human serum by isotope-dilution liquid chromatography-tandem mass spectrometry

期刊: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021; 464 ()

Glycocholic acid (GCA) is an important identified biomarker for various hepatobiliary diseases. However, results obtained from routine clinical measur......

A gated integration method for the detection of unevenly distributed ions bunches in laser resonant ionization mass spectrometry

期刊: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021; 465 ()

In laser resonance ionization mass spectrometry (RIMS) systems, pulsed lasers are usually employed to excite and ionize the elements of interest. Ther......

A rapid LC-MS/MS method for simultaneous determination of nicotine and its key derivatives including hydroxylation isomers

期刊: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021; 468 ()

A rapid high pressure liquid chromatography coupled with tandem mass spectrometry method (LC-MS/ MS) was developed for simultaneously determining nico......

An improved peak detection algorithm in mass spectra combining wavelet transform and image segmentation

期刊: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021; 465 ()

Peak detection is a crucial step in the analysis of mass spectrometry data. However, the measured spectrum inevitably contains random noise and alteri......

A new method for the simultaneous determination of urinary NNAL and cotinine concentrations using HILIC-MS/MS coupled with PRiME HLB SPE

期刊: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021; 465 ()

Urinary cotinine and NNAL are the biomarkers of tobacco smoke exposure and tobacco specific nitrosamines (TSNAs), respectively. A new method for the s......

Rapid identification of illegal drugs and explosives using resonance excitation in miniaturized photoionization ion trap mass spectrometry

期刊: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021; 467 ()

Illegal drugs and the explosives are harmful chemicals that present both social and national security issues. Existing analytical instruments and meth......

Effect of sampling modes on the discrimination of commercial gasolines using direct analysis in real time mass spectrometry

期刊: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021; 463 ()

The identification and classification of gasolines are crucial in a forensic context because direct evidences are provided on gasoline adulteration or......

Quantitative evaluation and regulation of cold-ion system intrinsic micromotion by numerical simulation

期刊: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021; 468 ()

The intrinsic micromotion of radio-frequency (RF) trapped three-dimensional (3D) cold ion systems plays an important role in the trapping, cooling, an......

MALDI-MS imaging of lipids and small molecules in rat brain tissue based on graphene oxide film pre-coated matrix

期刊: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021; 464 ()

In the study, single-layer graphene oxide (SLGO) was adsorbed on a conductive glass surface to prepare a uniform thin film. We used this film as the p......

Non-target geographic region discrimination of Cabernet Sauvignon wine by direct analysis in real time mass spectrometry with chemometrics methods

期刊: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021; 464 ()

Direct analysis in real time integrated with high-resolution mass spectrometry (DART-HRMS) was developed in geographic region (i.e., altitude range an......

Qualitative and quantitative analysis of opiate and related metabolites in human urine samples by UPLC-MS/MS

期刊: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021; 464 ()

Although opioids such as morphine are regarded as essential drugs for clinical pain treatment, they are forbidden in athletic events. To maintain the ......

Structure elucidation of new kinds of bacitracin sulfonic acid based on high performance liquid chromatography-quadrupole time of flight-tandem mass spectrometry

期刊: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021; 461 ()

Bacitracin is a mixture of antimicrobial peptides. Although the structures of bacitracins have been fully studied, the structure elucidation of the ox......

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