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The Two Formyl Peptide Receptors Differently Regulate GPR84-Mediated Neutrophil NADPH Oxidase Activity

期刊: JOURNAL OF INNATE IMMUNITY, 2021; 13 (4)

Neutrophils express the two formyl peptide receptors (FPR1 and FPR2) and the medium-chain fatty acid receptor GPR84. The FPRs are known to define a hi......

Neuronal Dual Leucine Zipper Kinase Mediates Inflammatory and Nociceptive Responses in Cyclophosphamide-Induced Cystitis

期刊: JOURNAL OF INNATE IMMUNITY, 2021; 13 (5)

Interstitial cystitis is associated with neurogenic inflammation and neuropathic bladder pain. Dual leucine zipper kinase (DLK) expressed in sensory n......

Intestinal Epithelial Cell-Derived CD83 Contributes to Regulatory T-Cell Generation and Inhibition of Food Allergy

期刊: JOURNAL OF INNATE IMMUNITY, 2021; 13 (5)

The mechanism of generation of antigen-specific regulatory T cells (Treg) is not fully understood yet. This study aimed to investigate the role of int......

A Thermally Stable Protein EPP1 of Corn Borer Ostrinia furnacalis Regulates Hemocytic Encapsulation

期刊: JOURNAL OF INNATE IMMUNITY, 2021; 13 (5)

Encapsulation is a vital cellular immune reaction of host insects against endoparasitoids; however, how encapsulation is regulated is still unclear. U......

Positive Feedback Loop of Long Noncoding RNA OASL-IT1 and Innate Immune Response Restricts the Replication of Zika Virus in Epithelial A549 Cells

期刊: JOURNAL OF INNATE IMMUNITY, ; ()

Expression of host noncoding RNAs and coding mRNAs is significantly altered by viral infection. In the current study, we screened the transcriptional ......

PolyADP-Ribosylation of NFATc3 and NF-kappa B Transcription Factors Modulate Macrophage Inflammatory Gene Expression in LPS-Induced Acute Lung Injury

期刊: JOURNAL OF INNATE IMMUNITY, 2021; 13 (2)

Pulmonary macrophages play a critical role in the recognition of pathogens, initiation of host defense via inflammation, clearance of pathogens from t......

Prostaglandin E-2 Regulates Activation of Mouse Peritoneal Macrophages by Staphylococcus aureus through Toll-Like Receptor 2, Toll-Like Receptor 4, and NLRP3 Inflammasome Signaling

期刊: JOURNAL OF INNATE IMMUNITY, 2020; 12 (2)

Prostaglandin E-2 (PGE(2)), an essential endogenous lipid mediator for normal physiological functions, can also act as an inflammatory mediator in pat......

Survivin Impairs the Apoptotic Machinery in CD4(+) T Cells of Patients with Ulcerative Colitis

期刊: JOURNAL OF INNATE IMMUNITY, 2020; 12 (3)

Background: The increase in CD4(+) T cell infiltration and overproduction of CD4(+) T cell-associated cytokines have been observed in the inflamed col......

Activation of Toll-Like Receptor 3 Induces Interleukin-1 Receptor Antagonist Expression by Activating the Interferon Regulatory Factor 3

期刊: JOURNAL OF INNATE IMMUNITY, 2020; 12 (4)

Toll-like receptor 3 (TLR3) is a sensor of endogenous cell necrosis during the process of acute inflammation. Interleukin (IL)-1 receptor antagonist (......

Aryl Hydrocarbon Receptor Modulates the Expression of TNF-alpha and IL-8 in Human Sebocytes via the MyD88-p65NF-kappa B/p38MAPK Signaling Pathways

期刊: JOURNAL OF INNATE IMMUNITY, 2019; 11 (1)

Activation of Toll-like receptor (TLR)-2 and subsequent inflammatory response contribute to lesion development in acne vulgaris. A cross-talk between ......

JIF:4.09

Cyclic Dimeric Guanosine Monophosphate: Activation and Inhibition of Innate Immune Response

期刊: JOURNAL OF INNATE IMMUNITY, 2019; 11 (3)

Cyclic dimeric guanosine monophosphate (c-di-GMP) is a universally conserved second messenger that contributes to the pathogenicity of numerous bacter......

JIF:4.09

Human Cervical Epithelial Cells Release Antiviral Factors and Inhibit HIV Replication in Macrophages

期刊: JOURNAL OF INNATE IMMUNITY, 2019; 11 (1)

The female reproductive tract is a major site of HIV sexual transmission. We here examined whether human cervical epithelial cells (HCEs) can be immun......

JIF:4.09

Differential Kinetics of Aspergillus nidulans and Aspergillus fumigatus Phagocytosis

期刊: JOURNAL OF INNATE IMMUNITY, 2018; 10 (2)

Invasive aspergillosis mainly occurs in immunocompromised patients and is commonly caused by Aspergillus fumigatus, while A. nidulans is rarely the ca......

JIF:4.09

PLA1A Participates in the Antiviral Innate Immune Response by Facilitating the Recruitment of TANK-Binding Kinase 1 to Mitochondria

期刊: JOURNAL OF INNATE IMMUNITY, 2018; 10 (4)

As a key molecule in the antiviral innate immune response, the activation of TANK-binding kinase 1 (TBK1) is under tight regulation. In this report, w......

JIF:4.09

Inducible GBP5 Mediates the Antiviral Response via Interferon-Related Pathways during Influenza A Virus Infection

期刊: JOURNAL OF INNATE IMMUNITY, 2017; 9 (4)

Guanylate binding protein (GBP) 5 belongs to the GBP family, which is involved in important cellular processes, including signal transduction, transla......

JIF:3.84

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