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Brain functional connectivity patterns in focal cortical dysplasia related epilepsy

期刊: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2021; 87 ()

Objective: Focal cortical dysplasia (FCD) appears to be strongly associated with intractable epilepsy. Although patients with FCD are candidates for e......

Electroclinical features of MEF2C haploinsufficiency-related epilepsy: A multicenter European study

期刊: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2021; 88 ()

Purpose: Epilepsy is a main manifestation in the autosomal dominant mental retardation syndrome caused by heterozygous variants in MEF2C. We aimed to ......

Altered peri-seizure EEG microstate dynamics in patients with absence epilepsy

期刊: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2021; 88 ()

Objective: To investigate whether the parameters of EEG microstates changed before and after an absence seizure episode. Methods: AE patients with a c......

Aberrant basal ganglia-thalamo-cortical network topology in juvenile absence epilepsy: A resting-state EEG-fMRI study

期刊: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2021; 84 ()

Purpose: The underlying pathophysiology of juvenile absence epilepsy (JAE) is unclear. Since cortical and subcortical brain regions are thought to be ......

Astroglial connexins in epileptogenesis

期刊: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2021; 84 ()

The astroglial network connected through gap junctions assembling from connexins physiologically balances the concentrations of ions and neurotransmit......

Development and external validation of a predictive nomogram model of posttraumatic epilepsy: A retrospective analysis

期刊: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2021; 88 ()

Objective: We aimed to develop and validate a predictive model of posttraumatic epilepsy (PTE). Methods: The training cohort was patients registered a......

Neurodevelopmental disorder caused by a truncating de novo variant of IRF2BPL

期刊: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2021; 84 ()

Background: Mutations in the IRF2BPL gene can cause neurodevelopmental disorders. We describe the clinical and genetic characteristics of a Chinese pa......

Clinical characteristics and treatment outcomes of pediatric patients with postencephalitic epilepsy characterized by epileptic spasms

期刊: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2021; 84 ()

Purpose: Viral encephalitis (VE) or bacterial meningoencephalitis (BME) in early childhood may cause brain injury and neurological sequelae, including......

The chapeau de gendarme sign can be evoked by lateral prefrontal epileptic seizures

期刊: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2021; 87 ()

Purpose: The ?chapeau de gendarme? (CDG) sign, characterised by a symmetric down-turned mouth, has been considered as a semiological hallmark of focal......

Efficacy of phenobarbital in treating elderly epilepsy patients in rural northeast China: A community-based intervention trial

期刊: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2021; 89 ()

Object: To provide information on the characteristics of elderly epilepsy patients in rural Northeast China. Method: Consecutive patients (aged >60......

Effects of double-dose statin therapy for the prevention of post-stroke epilepsy: A prospective clinical study

期刊: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2021; 88 ()

Background: To determine treatment effects on the incidence of post-stroke epilepsy (PSE) using different doses of statin, a prospective hospital-base......

Predictors and Long-term Outcome of Resective Epilepsy Surgery in Patients with Tuberous Sclerosis Complex: A Single-centre Retrospective Cohort Study

期刊: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2021; 88 ()

Objective: : To identify prognostic factors and long-term seizure outcomes for patients with tuberous sclerosis complex (TSC) who underwent resective ......

Comprehensive genetic, clinical and electrophysiological studies of familial cortical myoclonic tremor with epilepsy 1 highlight the role of gene configurations

期刊: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2021; 87 ()

Objectives: Two configurations of TTTTA/TTTCA expansion in SAMD12 have been identified in familial cortical myoclonic tremor with epilepsy type 1 (FCM......

Correlation of Seizure Increase and COVID-19 Outbreak in Adult Patients with Epilepsy: Findings and Suggestions from a Nationwide Multi-centre Survey in China

期刊: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2021; 88 ()

Objectives: To investigate the impact of the COVID-19 outbreak on the behaviours, mental health and seizure control of adult patients with epilepsy (P......

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