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Inhibition of microRNA-143-3p Attenuates Cerebral Ischemia/Reperfusion Injury by Targeting FSTL1

期刊: NEUROMOLECULAR MEDICINE, ; ()

MicroRNA (miRNA) miR-143-3p has been reported to participate in the progression of myocardial ischemia/reperfusion (I/R) injury, but its function in c......

LncRNA LINC00689 Promotes the Tumorigenesis of Glioma via Mediation of miR-526b-3p/IGF2BP1 Axis

期刊: NEUROMOLECULAR MEDICINE, ; ()

Glioma ranks first among the aggressive brain tumors all over the world. LncRNA LINC00689 has been confirmed to play key roles in the progression of c......

Proteomic Analysis of Perihematoma Tissue from Patients with Intracerebral Hemorrhage Using iTRAQ-Based Quantitative Proteomics

期刊: NEUROMOLECULAR MEDICINE, ; ()

Intracerebral hemorrhage is a complicated disorder with limited proven prognostic and therapeutic targets and elusive mechanisms. With proteomic metho......

VEGF Modulates the Neural Dynamics of Hippocampal Subregions in Chronic Global Cerebral Ischemia Rats

期刊: NEUROMOLECULAR MEDICINE, ; ()

Theta and gamma rhythms in hippocampus are important to cognitive performance. The cognitive impairments following cerebral ischemia is linked with th......

Association of Single Nucleotide Polymorphism at rs2275294 in the ZNF512B Gene with Prognosis in Amyotrophic Lateral Sclerosis

期刊: NEUROMOLECULAR MEDICINE, ; ()

The aim of this study is to explore whether the single nucleotide polymorphism rs2275294 in the ZNF512B gene is related to the length of survival of p......

Extract of Polygala tenuifolia, Angelica tenuissima, and Dimocarpus longan Reduces Behavioral Defect and Enhances Autophagy in Experimental Models of Parkinson's Disease

期刊: NEUROMOLECULAR MEDICINE, ; ()

The 20% ethanol extract of Polygala tenuifolia, Angelica tenuissima, and Dimocarpus longan (WIN-1001X) was derived from a modified version of Korean t......

Ultrastructural Characteristics of DHA-Induced Pyroptosis

期刊: NEUROMOLECULAR MEDICINE, 2020; 22 (2)

Microglial cells are resident macrophages of the central nervous system (CNS) that respond to bioactive lipids such as docosahexaenoic acid (DHA). Low......

Safflower Yellow Improves Synaptic Plasticity in APP/PS1 Mice by Regulating Microglia Activation Phenotypes and BDNF/TrkB/ERK Signaling Pathway

期刊: NEUROMOLECULAR MEDICINE, 2020; 22 (3)

Alzheimer's disease (AD) is a common neurodegenerative disease that is always accompanied by synaptic loss in the brain. Safflower yellow (SY) is the ......

Overexpression miR-486-3p Promoted by Allicin Enhances Temozolomide Sensitivity in Glioblastoma Via Targeting MGMT

期刊: NEUROMOLECULAR MEDICINE, 2020; 22 (3)

Glioblastoma is the most common primary tumor of the central nervous system that develops chemotherapy resistance. Previous studies showed that Allici......

alpha-Arbutin Protects Against Parkinson's Disease-Associated Mitochondrial Dysfunction In Vitro and In Vivo

期刊: NEUROMOLECULAR MEDICINE, 2020; 22 (1)

Parkinson's disease (PD), the most common neurodegenerative movement disorder, is characterized by the progressive loss of dopaminergic neurons in sub......

CSF sAPP alpha and sAPP beta levels in Alzheimer's Disease and Multiple Other Neurodegenerative Diseases: A Network Meta-Analysis

期刊: NEUROMOLECULAR MEDICINE, 2020; 22 (1)

The soluble amyloid protein procurer alpha (sAPP alpha) and beta (sAPP beta) have been postulated as promising new cerebrospinal fluid (CSF) biomarker......

Tyrosine Hydroxylase Gene Polymorphisms Contribute to Opioid Dependence and Addiction by Affecting Promoter Region Function

期刊: NEUROMOLECULAR MEDICINE, 2020; 22 (3)

Mounting evidence shows that drug dependence involves the complex interplay between genetics and the environment. Tyrosine hydroxylase (TH) is the rat......

Gnaq Protects PC12 Cells from Oxidative Damage by Activation of Nrf2 and Inhibition of NF-kB

期刊: NEUROMOLECULAR MEDICINE, 2020; 22 (3)

Reactive oxygen species (ROS) are continuously produced as byproducts of aerobic metabolism. Oxidative stress (OS) plays an important role in the occu......

Downregulation of Microrna-421 Relieves Cerebral Ischemia/Reperfusion Injuries: Involvement of Anti-apoptotic and Antioxidant Activities

期刊: NEUROMOLECULAR MEDICINE, 2020; 22 (3)

Reperfusion after cerebral ischemia causes additional ischemic injuries due to sudden recovery of blood supply. It usually produces excessive reactive......

miR-146a Mimics Ameliorates Traumatic Brain Injury Involving JNK and NF-kappa B Signaling Pathway

期刊: NEUROMOLECULAR MEDICINE, 2020; 22 (4)

Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality among the world, while the advance of TBI management is rather li......

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