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A Metabonomics Study of Guan-Xin-Shu-Tong Capsule against Diet-Induced Hyperlipidemia in Rats

期刊: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2021; 47 (2)

Guan-Xin-Shu-Tong capsule is a widely used traditional Chinese medicine for the treatment of cardiovascular diseases. However, little knowledge about ......

Synthesis and Bio-Evaluation of N-Benzylpiperidine-8-Hydroxyquinoline Derivatives as Potential Cholinesterase Inhibitors, Metal Ion Chelators and Calcium Channel Blockers

期刊: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2021; 47 (2)

A new series of N-benzylpiperidine 8-hydroxyquinoline derivatives were synthesized and evaluated as cholinesterase inhibitors, metal ion chelators and......

Virtual Screening of Antimicrobial Agents from Medicinal Plants

期刊: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2021; 47 (4)

Discovery of new antimicrobial agents is an urgent need to fight emerging antibiotic resistance. Auxiliary pathways such as metabolism-related and str......

Cytotoxic Activities and QSAR Studies of Diterpenoid Isosteviol Derivatives as Anti-Esophageal Agents

期刊: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2021; 47 (1)

The cytotoxicity of isosteviol and its twenty derivatives on three human tumor cell lines (ECA-109, MCF-7 and B16-F10) were evaluated. The results dem......

Inhibitory Evaluation and Molecular Docking Analysis of Benzenesulfonamides on Carbonic Anhydrase II

期刊: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2021; 47 (1)

Sulfonamides is an important class of compounds, which can be used as carbonic anhydrase inhibitors. Nine different benzenesulfonamide compounds were ......

Transcriptome Profiles in the Spleen of the Chinese Giant Salamander (Andrias davidianus) Challenged with Citrobacter freundii

期刊: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2021; 47 (1)

The Chinese giant salamander (Andrias davidianus) is one of the most important ecological breeding species with distinct characteristics and is cultur......

Synthesis and Acaricidal Activity of Aryl-Spirobutyrolactone Derivatives against Spider Mites under Greenhouse and Field Conditions

期刊: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2021; 47 (1)

Propesticides play an important role in modern agrochemicals research and development. In the controlling of harmful insects and mites in agriculture,......

A Novel 2-Phenyl-1,2,3-Triazole Derived Fluorescent Probe for Recyclable Detection of Al(3+)in Aqueous Medium and Its Application

期刊: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2020; 46 (4)

Abstrast -A novel 2-phenyl-1,2,3-triazole derived fluorescent probeHPTC((2-hydroxybenzylidene)-2-phenyl-2H-1,2,3-triazole-4-carbohydrazide) has been d......

Structural Organization of the Active Center of Unmodified Recombinant Sulfatase from the Mycelial Fungi Fusarium proliferatum LE1

期刊: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2020; 46 (4)

Sulfatases catalyze the hydrolysis of sulfuric acid esters and play a key role in a number of biological processes of both higher eukaryotes and proka......

Molecular Characterization and Expression Patterns of Shabby-Related Kinase (MmSK) Gene of Mulberry (Morus multicaulis)

期刊: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2020; 46 (5)

Shaggy-related protein kinase (SK) plays important roles in the plant growth development, signal transduction, abiotic stress and biotic stress and su......

Synthesis of Novel Chalcone-Based L-Homoserine Lactones and Their Quorum Sensing Inhibitory Activity Evaluation

期刊: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2020; 46 (2)

Two novel series of chalcone-based homoserine lactones were synthesized and their quorum sensing (QS) inhibitory activity was evaluated against Pseudo......

Essential Structural Profile of Novel Adenosine Derivatives as Antiplatelet Aggregation Inhibitors Based on 3D-QSAR Analysis Using CoMFA, CoMSIA, and SOMFA

期刊: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2020; 46 (3)

In this study, comparative molecular field analysis (CoMFA), comparative molecular similarity indices analysis (CoMSIA), and the self-organizing molec......

In Vitro Anti-HIV Effect of Voacamine fromVoacanga africanaStapf Based on the SPRi Experiment

期刊: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2020; 46 (3)

AIDS/HIV is a serious life-threatening and public health problem that urges for new antiviral drugs to control. A bis-indole alkaloid voacamine has be......

Identification and Characteristics of Batrachuperus karlschmidti miRNA Using Illumina Deep Sequencing

期刊: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2020; 46 (2)

MicroRNAs (miRNAs) play critical roles in regulating many biological processes of eukaryotes. Batrachuperus karlschmidti, as an endangered amphibian s......

Identification and Characteristics of Conserved miRNA in Testis Tissue from Chinese Giant Salamander (Andrias davidianus) by Deep Sequencing

期刊: RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2019; 45 (2)

MicroRNAs (miRNAs) are a family of approximate to 22-nucleotide, non-coding, single-stranded RNA molecules, which are considered as key regulators of ......

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