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Dimethyloxaloylglycine Increases the Bone Healing Capacity of Adipose-Derived Stem Cells by Promoting Osteogenic Differentiation and Angiogenic Potent
introduction
STEM CELLS AND DEVELOPMENT
Dimethyloxaloylglycine (DMOG) is a cellpermeable prolyl-4-hydroxylase inhibitor, which can activate the expression ofHIF-1ain cells at normal oxygen tension.
Dimethyloxaloylglycine Increases the Bone Healing Capacity of Adipose-Derived Stem Cells by Promoting Osteogenic Differentiation and Angiogenic Potent
introduction
STEM CELLS AND DEVELOPMENT
In previous studies, by activating the expression of HIF-1a, DMOG has been successfully used to attenuate postischemic myocardial injury and renal injury in remnant kidney, induce angiogenesis in ischemic skeletal muscles, and provide neuroprotection in a middle cerebral artery occlusion model.