笔记详情
标题
TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development
内容
TRAIL is a promising anticancer agent due to its ability to selectively induce apoptosis in established tumor cell lines but not nontransformed cells. Herein, we demonstrate a role for the apoptosis-inducing TRAIL receptor (TRAIL-R) as a metastasis suppressor.
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来源
J Clin Invest. 2008 January 2; 118(1): 100–110
类别
领域
Oncology - Medical
关键词
暂未填写
