Atrasentan for the treatment of diabetic nephropathy

Egido, J; Rojas-Rivera, J; Mas, S; Ruiz-Ortega, M; Sanz, AB; Parra, EG; Gomez-Guerrero, C

Egido, J (reprint author), Univ Autonoma Madrid, Univ Hosp Fdn Jimenez Diaz, Div Nephrol & Hypertens, Renal Vasc & Diabet Res Lab, Madrid, Spain.

EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2017; 26 (6): 741

Abstract

Introduction: Endothelin-1 (ET-1) is the most potent vasoconstrictor, and is involved in the renal regulation of salt and water homeostasis. When prod......

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