Structural basis for the reaction cycle of DASS dicarboxylate transporters

Sauer, DB; Trebesch, N; Marden, JJ; Cocco, N; Song, JM; Koide, A; Koide, S; Tajkhorshid, E; Wang, DN

Wang, DN (corresponding author), NYU, Sch Med, Skirball Inst Biomol Med, New York, NY 10016 USA.; Wang, DN (corresponding author), NYU, Sch Med, Dept Cell Biol, New York, NY 10016 USA.; Tajkhorshid, E (corresponding author), Univ Illinois, NIH Ctr Macromol Modeling & Bioinformat, Beckman Inst Adv Sci & Technol, Dept Biochem, Urbana, IL 61801 USA.; Tajkhorshid, E (corresponding author), Univ Illinois, Ctr Biophys & Quantitat Biol, Urbana, IL 61801 USA.

ELIFE, 2020; 9 ():

Abstract

Citrate, a-ketoglutarate and succinate are TCA cycle intermediates that also play essential roles in metabolic signaling and cellular regulation. Thes......

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