A rapid procedure to generate stably transfected HEK293 suspension cells for recombinant protein manufacturing: Yield improvements, bioreactor production and downstream processing

Dash, S; Farnós, O; Yang, ZY; Perumal, AS; Fulber, JPC; Venereo-Sánchez, A; Leclerc, D; Kamen, AA

Kamen, AA (通讯作者),McGill Univ, Dept Bioengn, McConnell Engn Bldg,Room 363 3480 Rue Univ, Montreal, PQ H3A 2K6, Canada.

PROTEIN EXPRESSION AND PURIFICATION, 2023; 210 ():

Abstract

The human cell line HEK293 is one of the preferred choices for manufacturing therapeutic proteins and viral vectors for human applications. Despite it......

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