A novel Notch1 missense mutation (C1133Y) in the Abruptex domain exhibits enhanced proliferation and invasion in oral squamous cell carcinoma

Zheng, Y; Wang, Z; Ding, X; Zhang, W; Li, G; Liu, LK; Wu, HM; Gu, WY; Wu, YN; Song, XM

Song, XM (reprint author), Nanjing Med Univ, Key Lab Oral Dis Jiangsu Prov, 140 Hanzhong Rd, Nanjing 210029, Jiangsu, Peoples R China.; Song, XM (reprint author), Nanjing Med Univ, Stomatol Inst, 140 Hanzhong Rd, Nanjing 210029, Jiangsu, Peoples R China.;

CANCER CELL INTERNATIONAL, 2018; 18 ():

Abstract

Background: Notch1 has been regarded as a fundamental regulator in tissue differentiation and stem cell properties. Recently, Notch1 mutations have be......

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