Pathogenic germline IKZF1 variant alters hematopoietic gene expression profiles

Brodie, SA; Khincha, PP; Giri, N; Bouk, AJ; Steinberg, M; Dai, JQ; Jessop, L; Donovan, FX; Chandrasekharappa, SC; de Andrade, KC; Maric, I; Ellis, SR; Mirabello, L; Alter, BP; Savage, SA

Savage, SA (corresponding author), NCI, Clin Genet Branch, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.

COLD SPRING HARBOR MOLECULAR CASE STUDIES, 2021; 7 (4):

Abstract

IKZF1 encodes Ikaros, a zinc finger-containing transcription factor crucial to the development of the hematopoietic system. Germline pathogenic varian......

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