Sildenafil (Viagra((R))) Prevents Cox-1/TXA2 Pathway-Mediated Vascular Hypercontractility in ApoE(-/-) Mice

Leal, MAS; Dias, AT; Porto, ML; Brun, BF; Gava, AL; Meyrelles, SS; Gil-Longo, J; Campos-Toimil, M; Pereira, TMC; Vasquez, EC

Pereira, TMC; Vasquez, EC (reprint author), Vila Velha Univ, Pharmaceut Sci Grad Program, Vila Velha, ES, Brazil.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2017; 44 (5): 1796

Abstract

Background/Aims: The atherosclerotic apolipoprotein E-deficient (apoE(-/-)) mouse exhibits impaired vasodilation and enhanced vasoconstriction respons......

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