Modified recombinant human IgG1-Fc is superior to natural intravenous immunoglobulin at inhibiting immune-mediated demyelination

Baksmeier, C; Blundell, P; Steckel, J; Schultz, V; Gu, Q; Filipe, AD; Kohl, A; Linnington, C; Lu, DL; Dell, A; Haslam, S; Wang, JB; Czajkowsky, D; Goebels, N; Pleass, RJ

Pleass, RJ (corresponding author), Univ Liverpool Liverpool Sch Trop Med, Dept Trop Dis Biol, Liverpool L3 5QA, Merseyside, England.

IMMUNOLOGY, 2021; 164 (1): 90

Abstract

Intravenous immunoglobulin (IVIG) is an established treatment for numerous autoimmune conditions. Although Fc fragments derived from IVIG have shown e......

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