Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease

Sabatine, MS; Giugliano, RP; Keech, AC; Honarpour, N; Wiviott, SD; Murphy, SA; Kuder, JF; Wang, H; Liu, T; Wasserman, SM; Sever, PS; Pedersen, TR

Sabatine, MS (reprint author), Harvard Med Sch, Boston, MA 02115 USA.; Sabatine, MS (reprint author), Brigham & Womens Hosp, TIMI Study Grp, Div Cardiovasc Med, 60 Fenwood Rd, Boston, MA 02115 USA.

NEW ENGLAND JOURNAL OF MEDICINE, 2017; 376 (18): 1713

Abstract

BACKGROUND Evolocumab is a monoclonal antibody that inhibits proprotein convertase subtilisin-kexin type 9 (PCSK9) and lowers low-density lipoprotein ......

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