AKT Hyperactivation and the Potential of AKT-Targeted Therapy in Diffuse Large B-Cell Lymphoma

Wang, JF; Xu-Monette, ZY; Jabbar, KJ; Shen, Q; Manyam, GC; Tzankov, A; Visco, C; Wang, J; Montes-Moreno, S; Dybkaer, K; Tam, W; Bhagat, G; Hsi, ED; van Krieken, JH; Ponzoni, M; Ferreri, AJM; Wang, S; Moller, MB; Piris, MA; Medeiros, LJ; Li, Y; Pham,

Young, KH (reprint author), Univ Texas MD Anderson Canc Ctr, Dept Hematopathol, Houston, TX 77030 USA.

AMERICAN JOURNAL OF PATHOLOGY, 2017; 187 (8): 1700

Abstract

AKT signaling is important for proliferation and survival of tumor cells. The clinical significance of AKT activation in diffuse large B-cell lymphoma......

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