Identification of novel inhibitors for TNF alpha, TNFR1 and TNF alpha-TNFR1 complex using pharmacophore-based approaches

Saddala, MS; Huang, H

Huang, H (reprint author), Univ Missouri, Mason Eye Inst, Dept Ophthalmol, Sch Med, One Hosp Dr,MA102C, Columbia, MO 65212 USA.

JOURNAL OF TRANSLATIONAL MEDICINE, 2019; 17 ():

Abstract

BackgroundTumor necrosis factor alpha (TNF alpha) is a multifunctional cytokine with a potent pro-inflammatory effect. It is a validated therapeutic t......

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