Conserved cholesterol-related activities of Dispatched 1 drive Sonic hedgehog shedding from the cell membrane

Ehring, K; Manikowski, D; Goretzko, J; Froese, J; Gude, F; Jakobs, P; Rescher, U; Kirchhefer, U; Grobe, K

Grobe, K (通讯作者),Univ Munster, Inst Physiol Chem & Pathobiochem, Waldeyerstr 15, D-48149 Munster, Germany.

JOURNAL OF CELL SCIENCE, 2022; 135 (5):

Abstract

The Sonic hedgehog (Shh) pathway controls embryonic development and tissue homeostasis after birth. Long-standing questions about this pathway include......

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