Change in Topoisomerase 1-Positive Circulating Tumor Cells Affects Overall Survival in Patients with Advanced Breast Cancer after Treatment with Etirinotecan Pegol

Rugo, HS; Cortes, J; Awada, A; O'Shaughnessy, J; Twelves, C; Im, SA; Hannah, A; Lu, L; Sy, S; Caygill, K; Zajchowski, DA; Davis, DW; Tagliaferri, M; Hoch, U; Perez, EA

Hoch, U (reprint author), Nektar Therapeut, 455 Mission Bay Blvd South, San Francisco, CA 94158 USA.

CLINICAL CANCER RESEARCH, 2018; 24 (14): 3348

Abstract

Purpose: Preplanned exploratory analyses were performed to identify biomarkers in circulating tumor cells (CTC) predictive of response to the topoisom......

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