Interaction of Functionalized Naphthalenophanes with Abasic Sites in DNA: DNA Cleavage, DNA Cleavage Inhibition, and Formation of Ligand-DNA Adducts

Caron, C; Duong, XNT; Guillot, R; Bombard, S; Granzhan, A

Granzhan, A (reprint author), PSL Res Univ, CNRS UMR9187, INSERM U1196, Inst Curie, F-91405 Orsay, France.; Granzhan, A (reprint author), Univ Paris Saclay, CNRS UMR9187, INSERM U1196, Univ Paris Sud, F-91405 Orsay, France.

CHEMISTRY-A EUROPEAN JOURNAL, 2019; 25 (8): 1949

Abstract

Ligands interacting with abasic (AP) sites in DNA may generate roadblocks in base-excision DNA repair (BER) due to indirect inhibition of DNA repair e......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索