Retinal and Systemic Toxicity of Vigabatrin Is Driven by the S-Enantiomer in the Long Evans Rat

Rasmussen, AD; Truchot, N; Dyssegaard, A; Fant, P

Rasmussen, AD (通讯作者)，H Lundbeck & Co AS, Ottiliavej 9, DK-2500 Valby, Denmark.

TOXICOLOGIC PATHOLOGY, 2023; ():

Abstract

In this study, we assessed the toxicity and toxicokinetics of racemic vigabatrin and its S- and R-enantiomers (vigabatrin consists of 50:50% of the tw......

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