IL-17A mediates pyroptosis via the ERK pathway and contributes to steroid resistance in CRSwNP

Li, Y; Chang, LH; Huang, WQ; Bao, HW; Li, X; Chen, XH; Wu, HT; Yao, ZZ; Huang, ZZ; Weinberg, SE; Fang, DY; Zhang, YN; Zhang, GH

Zhang, YN; Zhang, GH (通讯作者),Sun Yat Sen Univ, Affiliated Hosp 3, Dept Otolaryngol Head & Neck Surg, 600 Tianhe Rd, Guangzhou 510630, Peoples R China.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2022; 150 (2): 337

Abstract

Background: Pyroptosis is closely related to inflammation. However, the molecular mechanisms and pathologic contributions of pyroptotic epithelial cel......

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