TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H2O2

Melo, EP; Lopes, C; Gollwitzer, P; Lortz, S; Lenzen, S; Mehmeti, I; Kaminski, CF; Ron, D; Avezov, E

Ron, D; Avezov, E (reprint author), Univ Cambridge, Cambridge Inst Med Res, Wellcome Trust MRC Inst Metab Sci, Cambridge Biomed Campus,Hills Rd, Cambridge CB2 0XY, England.; Ron, D; Avezov, E (reprint author), NIHR Cambridge Biomed Res Ctr, Cambridge Biom

BMC BIOLOGY, 2017; 15 ( ):

Abstract

Background: The fate of hydrogen peroxide (H2O2) in the endoplasmic reticulum (ER) has been inferred indirectly from the activity of ER-localized thio......

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