Prokaryotic Argonaute Protein from Natronobacterium gregoryi Requires RNAs To Activate for DNA Interference In Vivo

Xing, JN; Ma, LX; Cheng, XZ; Ma, JR; Wang, RY; Xu, K; Mymryk, JS; Zhang, ZY

Zhang, ZY (通讯作者)，Northwest A&F Univ, Coll Anim Sci & Technol, Key Lab Anim Genet Breeding & Reprod Shaanxi Prov, Yangling, Shaanxi, Peoples R China.;Mymryk, JS (通讯作者)，Univ Western Ontario, Dept Microbiol & Immunol Oncol & Otolaryngol, London, ON, Canada.

MBIO, 2022; 13 (2):

Abstract

We revealed the mechanism that explains how the NgAgo eliminates the invading foreign DNA and bacteriophage in bacterial cells at 37 degrees C, and by......

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