Design, synthesis, and biological evaluation of novel ubiquitin-activating enzyme inhibitors

Itoh, Y; Suzuki, M

Itoh, Y (reprint author), Kyoto Prefectural Univ Med, Grad Sch Med Sci, Sakyo Ku, 1-5 Shimogamohangi Cho, Kyoto 6060823, Japan.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018; 28 (16): 2723

Abstract

Ubiquitin-activating enzyme (E1), which catalyzes the activation of ubiquitin in the initial step of the ubiquitination cascade, is a potential therap......

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