De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK plus ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells

Babin, L; Darchen, A; Robert, E; Aid, Z; Borry, R; Soudais, C; Piganeau, M; De Cian, A; Giovannangeli, C; Bawa, O; Rigaud, C; Scoazec, JY; Couronne, L; Veleanu, L; Cieslak, A; Asnafi, V; Sibon, D; Lamant, L; Meggetto, F; Mercher, T; Brunet, E

Brunet, E (通讯作者)，Univ Paris Saclay, Equipe Labellisee Ligue Canc, Lab Genome Dynam Immune Syst, Inst Imagine,Univ Paris,INSERM UMR 1163, Paris, France.;Mercher, T (通讯作者)，Univ Paris Saclay, Equipe Labellisee Ligue Canc, Gustave Roussy Canc Campus, OPALE Carnot Inst,INSERM Unite U1170,Programme PE, 114 Rue Edouard Vaillant, F-94805 Villejuif, France.

MOLECULAR CANCER, 2022; 21 (1):

Abstract

Background Anaplastic large cell lymphoma positive for ALK (ALK+ ALCL) is a rare type of non-Hodgkin lymphoma. This lymphoma is caused by chromosomal ......

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