Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo inflammation

Domingues, N; Gaifem, J; Matthiesen, R; Saraiva, DP; Bento, L; Soares, MIL; Sampaio, J; Klose, C; Surma, MA; Almeida, MS; Rodrigues, G; Goncalves, PA; Ferreira, J; Melo, RGE; Pedro, LM; Simons, K; Marques, ARA; Melo, TMVDP; Cabral, MG; Jacinto, A; Silvestre, R; Vaz, W; Vieira, OV

Vieira, OV (通讯作者),Univ Nova Lisboa, Fac Ciencias Med FCM, NOVA Med Sch NMS, iNOVA4Health, Lisbon, Portugal.

JOURNAL OF LIPID RESEARCH, 2023; 64 (9):

Abstract

Oxidation of PUFAs in LDLs trapped in the arterial intima plays a critical role in athero-sclerosis. Though there have been many studies on the athero......

Full Text Link