Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank

Jurgens, SJ; Choi, SH; Morrill, VN; Chaffin, M; Pirruccello, JP; Halford, JL; Weng, LC; Nauffal, V; Roselli, C; Hall, AW; Oetjens, MT; Lagerman, B; VanMaanen, DP; Center, RG; Aragam, KG; Lunetta, KL; Haggerty, CM; Lubitz, SA; Ellinor, PT

Ellinor, PT (通讯作者)，Broad Inst MIT & Harvard, Cardiovasc Dis Initiat, Cambridge, MA 02142 USA.;Ellinor, PT (通讯作者)，Massachusetts Gen Hosp, Cardiovasc Res Ctr, Boston, MA 02114 USA.;Ellinor, PT (通讯作者)，Massachusetts Gen Hosp, Demoulas Ctr Cardiac Arrhythmias, Boston, MA 02114 USA.

NATURE GENETICS, 2022; 54 (3): 240

Abstract

Cardiometabolic diseases are the leading cause of death worldwide. Despite a known genetic component, our understanding of these diseases remains inco......

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