A study of ruxolitinib response-based stratified treatment for pediatric hemophagocytic lymphohistiocytosis

Zhang, Q; Zhao, YZ; Ma, HH; Wang, D; Cui, L; Li, WJ; Wei, A; Wang, CJ; Wang, TY; Li, ZG; Zhang, R

Li, ZG (通讯作者),Capital Med Univ, Beijing Childrens Hosp, Natl Ctr Childrens Hlth, Beijing Pediat Res Inst,Hematol Dis Lab, 56 Nan Lishi Rd, Beijing 100045, Peoples R China.;Wang, TY; Zhang, R (通讯作者),Capital Med Univ, Beijing Childrens Hosp, Hematol Ctr, Natl Ctr Childrens Hlth, 56 Nan Lishi Rd, Beijing 100045, Peoples R China.

BLOOD, 2022; 139 (24): 3493

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a lethal disorder characterized by hyperinflammation. Recently, ruxolitinib (RUX), targeting key cytokines......

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