Ropeginterferon alpha-2b targets JAK2V617F-positive polycythemia vera cells in vitro and in vivo

Verger, E; Soret-Dulphy, J; Maslah, N; Roy, L; Rey, J; Ghrieb, Z; Kralovics, R; Gisslinger, H; Grohmann-Izay, B; Klade, C; Chomienne, C; Giraudier, S; Cassinat, B; Kiladjian, JJ

Kiladjian, JJ (reprint author), Hop St Louis, AP HP, Ctr Invest Clin, Paris, France.; Kiladjian, JJ (reprint author), Inst Univ Hematol, Hop St Louis, INSERM UMRS 1131, Paris, France.; Kiladjian, JJ (reprint author), Univ Paris Diderot, Paris, France.

BLOOD CANCER JOURNAL, 2018; 8 ():

Abstract

Polycythemia vera is characterized by the acquisition of the JAK2V617F mutation. Recommended treatments include hydroxyurea and interferon-alpha. Seve......

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