Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus

Thomsen, K; Yokota, T; Hasan-Olive, MM; Sherazi, N; Fakouri, NB; Desler, C; Regnell, CE; Larsen, S; Rasmussen, LJ; Dela, F; Bergersen, LH; Lauritzen, M

Thomsen, K (reprint author), Univ Copenhagen, Ctr Neurosci, Transneurogrp, Panum 07-4,Blegdamsvej 3, DK-2200 Copenhagen, Denmark.

NEUROBIOLOGY OF AGING, 2018; 61 (): 215

Abstract

Brain aging is accompanied by declining mitochondrial respiration. We hypothesized that mitochondrial morphology and dynamics would reflect this decli......

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