A methylation functional detection hepatic cell system validates correlation between DNA methylation and drug-induced liver injury

Wei, YQ; Huai, C; Zhou, CX; Gao, YQ; Chen, L; Zhou, W; Wei, MY; Qin, SY

Qin, SY (corresponding author), Shanghai Jiao Tong Univ, Minist Educ, Bio X Inst, Key Lab Genet Dev & Neuropsychiat Disorders, Shanghai 200030, Peoples R China.; Qin, SY (corresponding author), Jining Med Univ, Collaborat Innovat Ctr, Jining 272067, Shandong, Peoples R China.

PHARMACOGENOMICS JOURNAL, 2020; 20 (5): 717

Abstract

Drug-induced liver injury (DILI) is a life-threatening, adverse reaction to certain drugs. The onset and extent of DILI can vary drastically in differ......

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