Application of estimand framework in ICH E9 (R1) to vaccine trials

Fu, R; Li, HL; Wang, XL; Shou, Q; Wang, WWB

Fu, R (通讯作者),MSD, BARDS, Wangjing R&D Base, Bldg 21,Rongda Rd, Beijing 100012, Peoples R China.

JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 2023; 33 (4): 502

Abstract

Over the past decades, the primary interest in vaccine efficacy or immunogenicity evaluation mostly focuses on the biological effect of immunization i......

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