Structure-Based Analysis of Transient Interactions between Ketosynthase-like Decarboxylase and Acyl Carrier Protein in a Loading Module of Modular Polyketide Synthase

Chisuga, T; Murakami, S; Miyanaga, A; Kudo, F; Eguchi, T

Miyanaga, A; Eguchi, T (通讯作者)，Tokyo Inst Technol, Dept Chem, Tokyo 1528551, Japan.;Miyanaga, A (通讯作者)，Univ Tokyo, Grad Sch Agr & Life Sci, Bunkyo Ku, Tokyo 1138657, Japan.

ACS CHEMICAL BIOLOGY, 2023; 18 (6): 1398

Abstract

Ketosynthase-like decarboxylase (KSQ) domainsare widelydistributed in the loading modules of modular type I polyketide synthases(PKSs) and catalyze th......

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