BET Inhibition Enhances TNF-Mediated Antitumor Immunity

Wellinger, LC; Hogg, SJ; Newman, DM; Friess, T; Geiss, D; Michie, J; Ramsbottom, KM; Bacac, M; Fauti, T; Marbach, D; Jarassier, L; Thienger, P; Paehler, A; Cluse, LA; Kearney, CJ; Vervoort, SJ; Trapani, JA; Oliaro, J; Shortt, J; Ruefli-Brasse, A; Rohle, D; Johnstone, RW

Johnstone, RW (通讯作者)，Peter MacCallum Canc Ctr, Translat Hematol Program, 305 Grattan St, Melbourne, Vic 3000, Australia.;Rohle, D (通讯作者)，Ridgeline Discovery, Hochbergerstr 60C, CH-4055 Basel, Switzerland.

CANCER IMMUNOLOGY RESEARCH, 2022; 10 (1): 87

Abstract

Targeting chromatin binding proteins and modifying enzymes can concomitantly affect tumor cell proliferation and survival, as well as enhance antitumo......

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