Dihydropyrazothiazole derivatives as potential MMP-2/MMP-8 inhibitors for cancer therapy

Wang, ZC; Shen, FQ; Yang, MR; You, LX; Chen, LZ; Zhu, HL; Lu, YD; Kong, FL; Wang, MH

Wang, MH (reprint author), Nanjing Agr Univ, Coll Plant Protect, Dept Pesticide Sci, Nanjing 210095, Jiangsu, Peoples R China.; Kong, FL (reprint author), Jiangsu Agrochem Lab Co Ltd, Changzhou 213000, Peoples R China.; Lu, YD (reprint author), Nanjing Me

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018; 28 (23-24): 3816

Abstract

MMP-2/MMP-8 is established as one of the most important metalloenzymes for targeting cancer. A series of dihydropyrazothiazole derivatives (E1-E18) be......

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