Zn2+ modulates in vitro phase separation of TDP-43(2C) and mutant TDP-43(2C)-A315T C-terminal fragments of TDP-43 protein implicated in ALS and FTLD-TDP diseases-MedSci.cn

Zn2+ modulates in vitro phase separation of TDP-43(2C) and mutant TDP-43(2C)-A315T C-terminal fragments of TDP-43 protein implicated in ALS and FTLD-TDP diseases

Preethi, S; Bharathi, V; Patel, BK

Patel, BK (corresponding author), Indian Inst Technol Hyderabad, Dept Biotechnol, Sangareddy 502285, Telangana, India.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021; 176 (): 186

Abstract

TDP-43 proteinopathy is implicated in the neurodegenerative diseases, ALS and FTLD-TDP. Metal ion dyshomeostasis is observed in neurodegenerative dise......

Full Text Link

Links

科室
- - 订阅+
  - 更多科室
工具
服务

内科

外科

专科科室

热点

按科室浏览

临床工具

科研工具

其他工具

科研数智化

真实世界研究解决方案

数字化学术传播解决方案

其它

Zn2+ modulates in vitro phase separation of TDP-43(2C) and mutant TDP-43(2C)-A315T C-terminal fragments of TDP-43 protein implicated in ALS and FTLD-TDP diseases

科室

工具

服务