Discovery of novel pyrazole and pyrazolo[1,5-a]pyrimidine derivatives as cyclooxygenase inhibitors (COX-1 and COX-2) using molecular modeling simulation-MedSci.cn

Discovery of novel pyrazole and pyrazolo[1,5-a]pyrimidine derivatives as cyclooxygenase inhibitors (COX-1 and COX-2) using molecular modeling simulation

Ayman, R; Radwan, AM; Elmetwally, AM; Ammar, YA; Ragab, A

Ayman, R (通讯作者)，Al Azhar Univ, Fac Sci Girls, Dept Chem, Cairo 11754, Egypt.;Ammar, YA; Ragab, A (通讯作者)，Al Azhar Univ, Fac Sci Boys, Dept Chem, Cairo 11884, Egypt.

ARCHIV DER PHARMAZIE, 2023; 356 (2):

Abstract

Searching for effective and selective anti-inflammatory agents, our study involved designing and synthesizing new pyrazole and pyrazolo[1,5-a]pyrimidi......

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