The apelin-apelin receptor signaling pathway in fibroblasts is involved in tumor growth via p53 expression of cancer cells

Saiki, H; Hayashi, Y; Yoshii, S; Kimura, E; Nakagawa, K; Kato, M; Uema, R; Inoue, T; Sakatani, A; Yoshihara, T; Tsujii, Y; Shinzaki, S; Iijima, H; Takehara, T

Takehara, T (通讯作者)，Osaka Univ, Dept Gastroenterol & Hepatol, Grad Sch Med, 2-2 Yamadaoka, Suita, Osaka 5650871, Japan.

INTERNATIONAL JOURNAL OF ONCOLOGY, 2023; 63 (6):

Abstract

Cancer-associated fibroblasts (CAFs) are pivotal in tumor progression. TP53-deficiency in cancer cells is associated with robust stromal activation. T......

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