Machine Learning Techniques Outperform Conventional Statistical Methods in the Prediction of High Risk QTc Prolongation Related to a Drug-Drug Interaction

Van Laere, S; Muylle, KM; Dupont, AG; Cornu, P

Cornu, P (通讯作者)，Vrije Univ Brussel, Dept Pharmaceut & Pharmacol Sci FARM, Res Grp Clin Pharmacol & Clin Pharm KFAR, Laarbeeklaan 103, B-1090 Brussels, Belgium.;Cornu, P (通讯作者)，Univ Ziekenhuis Brussel, Dept Med Informat, Laarbeeklaan 103, B-1090 Brussels, Belgium.

JOURNAL OF MEDICAL SYSTEMS, 2022; 46 (12):

Abstract

In clinical practice, many drug therapies are associated with prolongation of the QT interval. In literature, estimation of the risk of prescribing dr......

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