PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability

Gryder, BE; Yohe, ME; Chou, HC; Zhang, XH; Marques, J; Wachtel, M; Schaefer, B; Sen, N; Song, Y; Gualtieri, A; Pomella, S; Rota, R; Cleveland, A; Wen, XY; Sindiri, S; Wei, JS; Barr, FG; Das, S; Andresson, T; Guha, R; Lal-Nag, M; Ferrer, M; Shern, JF;

Khan, J (reprint author), NIH, 37 Convent Dr,Bldg 37,Room 2016B, Bethesda, MD 20892 USA.

CANCER DISCOVERY, 2017; 7 (8): 884

Abstract

Alveolar rhabdomyosarcoma is a life-threatening myogenic cancer of children and adolescent young adults, driven primarily by the chimeric transcriptio......

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