Rational design and improvement of the dimerization-disrupting peptide selectivity between ROCK-I and ROCK-II kinase isoforms in cerebrovascular diseases

Gu, ZT; Yan, TT; Yan, FL

Yan, FL (corresponding author), Southeast Univ, Affiliated Zhongda Hosp, Sch Med, Dept Neurol, Nanjing 210009, Peoples R China.

JOURNAL OF MOLECULAR RECOGNITION, 2020; 33 (6):

Abstract

Human rho-associated coiled-coil forming kinases (ROCKs) ROCK-I and ROCK-II have been documented as attractive therapeutic targets for cerebrovascular......

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