Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

Abbosh, C; Birkbak, NJ; Wilson, GA; Jamal-Hanjani, M; Constantin, T; Salari, R; Le Quesne, J; Moore, DA; Veeriah, S; Rosenthal, R; Marafioti, T; Kirkizlar, E; Watkins, TBK; McGranahan, N; Ward, S; Martinson, L; Riley, J; Fraioli, F; Al Bakir, M; Gron

Swanton, C (reprint author), UCL, Canc Inst, Canc Res UK Lung Canc Ctr Excellence London & Man, Paul OGorman Bldg,72 Huntley St, London WC1E 6DD, England.; Swanton, C (reprint author), Francis Crick Inst, Translat Canc Therapeut Lab, 1 Midland Rd, London

NATURE, 2017; 545 (7655): 446

Abstract

The early detection of relapse following primary surgery for non-small-cell lung cancer and the characterization of emerging subclones, which seed met......

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