Resurrection of an ancient inflammatory locus reveals switch to caspase-1 specificity on a caspase-4 scaffold

Bibo-Verdugo, B; Joglekar, I; Giridhar, MNK; Ramirez, ML; Snipas, SJ; Clark, AC; Poreba, M; Salvesen, GS

Salvesen, GS (通讯作者)，Sanford Burnham Prebys Med Discovery Inst, La Jolla, CA 92037 USA.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2022; 298 (6):

Abstract

Pyroptosis is a mechanism of inflammatory cell death mediated by the activation of the prolytic protein gasdermin D by caspase-1, caspase-4, and caspa......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索