The TLR4-MyD88-NF-kappa B pathway is involved in sIgA-mediated IgA nephropathy

Zhang, JJ; Mi, YM; Zhou, RW; Liu, ZS; Huang, B; Guo, RX; Wang, PF; Lu, YR; Zhou, YL; Quan, SX

Zhang, JJ; Liu, ZS (corresponding author), Zhengzhou Univ, Dept Nephrol, Affiliated Hosp 1, Zhengzhou 450052, Peoples R China.; Zhang, JJ; Liu, ZS (corresponding author), Zhengzhou Univ, Res Inst Nephrol, Zhengzhou 450052, Peoples R China.; Liu, ZS (corresponding author), Key Lab Precis Diag & Treatment Chron Kidney Dis, Zhengzhou 450052, Peoples R China.; Liu, ZS (corresponding author), Natl Clin Med Res Ctr Kidney Dis, Core Unit, Zhengzhou 450052, Peoples R China.

JOURNAL OF NEPHROLOGY, 2020; 33 (6): 1251

Abstract

Previous studies have shown that secretory IgA (sIgA) was critically involved in IgA nephropathy (IgAN) immune responses. Toll-like receptors (TLRs), ......

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