Low-dose Dasatinib Ameliorates Hypertrophic Cardiomyopathy in Noonan Syndrome with Multiple Lentigines

Yi, JS; Perla, S; Huang, Y; Mizuno, K; Giordano, FJ; Vinks, AA; Bennett, AM

Yi, JS (通讯作者)，Yale Univ, Dept Pharmacol, Sch Med, New Haven, CT 06520 USA.

CARDIOVASCULAR DRUGS AND THERAPY, 2022; 36 (4): 589

Abstract

Purpose Noonan syndrome with multiple lentigines (NSML) is an autosomal dominant disorder presenting with hypertrophic cardiomyopathy (HCM). Up to 85%......

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