Catalpol Inhibits Tregs-to-Th17 Cell Transdifferentiation by Up-Regulating Let-7g-5p to Reduce STAT3 Protein Levels

Di, YX; Zhang, MF; Chen, YC; Sun, RN; Shen, MY; Tian, FX; Yang, P; Qian, FY; Zhou, LL

Zhou, LL (通讯作者),Nanjing Univ Chinese Med, Sch Pharm, Jiangsu Key Lab Pharmacol & Safety Evaluat Chines, 138 Xianlin Rd, Nanjing 210023, Peoples R China.

YONSEI MEDICAL JOURNAL, 2022; 63 (1): 56

Abstract

Purpose: Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease, and Th17 cells are key factors in the pathogenesis of human inflammatory ......

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