Metformin attenuates angiotensin II-induced cardiomyocyte hypertrophy by upregulating the MuRF1 and MAFbx pathway

Du, FW; Cao, YL; Ran, Y; Wu, Q; Chen, BL

Chen, BL (corresponding author), Guizhou Prov Peoples Hosp, Dept Cardiol, 83 Zhongshan Dong Rd, Guiyang 550002, Guizhou, Peoples R China.

EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2021; 22 (5):

Abstract

Pathological cardiac hypertrophy induced by aging and neurohumoral activation, such as angiotensin II (Ang II) activation, is an independent risk fact......

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